210+ Grey’s Anatomy Trivia Questions and Answers

Grey’s Anatomy is a TV show that has withstood the test of time. It has become the longest-running medical drama on set. Grey’s Anatomy is the kind of show that will inspire young viewers to venture into the field of Medicine. The cast makes surgeries and operational procedures appear so doable.

The script shows that it takes place in Seattle, Washington D.C. Apparently, it’s all done in Los Angeles. The Veterans Administration Sepulveda Ambulatory Care Center in North Hills, CA serves as the entrance to Grey-Sloan Memorial. The interior shots are filmed on soundstage at Prospect Studios in Los Feliz, CA.

Grey’s Anatomy Facts Trivia Questions and Answers

According to TV Guide, Justin Chambers’ character was an afterthought. Alex Karev came in after the Pilot was shot and became a long-lasting character on the show. His last role broke the hearts of fans as expressed on the internet.

With 18 Seasons already, Grey’s Anatomy is packed with so many interesting scenes that only astute viewers will be able to crack. Explore the trivia below!

1. How many seasons of “Grey’s Anatomy” are there?

18 and counting

 

2. What was the name of the hospital in the beginning?

Seattle Grace Hospital

 

3. When did “Grey’s Anatomy” start?

2005

 

4. What season is the musical episode in?

Season seven.

 

5. George O Malley gets which STD from Nurse Olivia?

Syphilis

 

6. What color scrubs do interns wear? What about attendings?

Light blue for interns, dark blue for attendings.

 

7. What kind of pregnancy did Cristina Yang have?

Ectopic pregnancy

 

8. Who usually says the voiceover narration in each episode?

Meredith.

 

9. Matthew proposed April with?

A flashmob

 

10. What is Derek’s signature saying?

“It’s a beautiful day to save lives.”

 

11. In what season did “Grey’s Anatomy” become the longest-running primetime medical drama?

Season 15.

 

12. What disease did Meredith Grey’s mother have?

Alzheimer’s

 

13. As of season 18, how many original cast members are still on the show?

Three.

 

14. What does George refuse to buy for Izzie and Meredith?

Tampons

 

15. Who are Meredith’s roommates?

Izzie and George.

 

16. In the first season, Derek tells Meredith his favorite color. What is it?

Indigo

 

17. Which intern has completely paid off their med school debt?

Izzie

 

18. How many seconds before did Erica Hanh’s patient gets admitted to the transplant list before Denny in the show?

17 seconds

 

19. What song is the pilot episode named after?

“A Hard Day’s Night” by The Beatles.

 

20. If you aren’t willing to keep looking for light in the darkest of places without stopping, even when it seems impossible, you will never succeed. Who said these lines on the show?

Amelia

 

21. Which two doctors are competing for chief of surgery?

Derek and Burke

 

22. What was the theme song in the first season?

“Cosy in the Rocket” by Psapp.

 

23. In season 5, the medical doctor visited which department for the first time?

Dermatology

 

24. Which major character is introduced at the very end of the season?

Addison Montgomery.

 

25. How many episodes does the first season have?

Nine

 

26. Which intern does Addison recruit to her specialty?

Izzie.

 

27. Which type of cancer was Izzie diagnosed with?

Metastatic Melanoma

 

28. Which intern successfully performs a “solo” surgery?

George

 

29. Who has to retake his exams?

George

 

30. Why does Meredith give her dog, Doc, to Derek and Addison?

George threatens to move out if Doc doesn’t.

 

31. What do you call a patient whose name is not known?

John Doe

 

32. Why does Derek punch Mark?

He sees Mark talking to Meredith when he first arrives.

 

33. What was the name of Mark Sloan’s first daughter?

Sloan Riley

 

34. Who gives Mark the “McSteamy” nickname?

Meredith

 

35. Which doctor secretly lives in the hospital?

Callie

 

36. Where was Denny’s body being sent to in Grey s Anatomy?

Memphis

 

37. Why does the hospital have a “prom”?

Because Webber’s niece is dying and will miss hers

 

38. What was the name of the man with who Dr. Bailey stayed when he was quarantined?

Omar

 

39. How does Addison find out that Meredith and Derek hooked up?

She finds Meredith’s underwear in Derek’s pocket.

 

40. How much money does Denny leave to Izzie?

$8.7 million

 

41. She was a consultant at Grey Sloan and wasn’t liked much?

Eliza Minnick

 

42. How many sisters does Derek have?

Four

 

43. Which character’s spinoff was “planted” during this season, and what is the show called?

Addison, “Private Practice.”

 

44. Who did Bailey hide with during the shooting at Seatle Grace?

Mary Portman

 

45. Which cast member earned an Emmy for their work on season three?

Katherine Heigl

 

46. Why does Izzie’s daughter come to Seattle Grace?

She needs leukemia treatment and a bone marrow transplant.

 

47. This patient believed she was a superhero because she never felt pain.

Megan Clover

 

48. What animal does Izzie “operate” on?

A deer

 

49. Whose sister becomes the main character in season 4?

Meredith’s sister Lexie.

50. How did a patient infamously end up with a bomb in their chest?

He accidentally shot himself with a World War II bazooka.

 

51. What is the name of the nurse who starts dating Derek?

Rose.

 

52. What was Grey s Anatomy originally going to be named?

Complications

 

53. Which doctor is the target of the nurses’ strike?

Mark

 

54. What is the name of the medical clinic that Bailey starts?

The Denny Duquette Memorial Clinic

 

55. Where did Cristina move to?

Switzerland

 

56. What was the name of the “surgery” doll that Ellis gave to Meredith?

Anatomy Jane

 

57. What bizarre implement injures Cristina?

A falling icicle.

 

58. What department do the characters hang out in to de-stress?

Dermatology

 

59. The show’s name is actually the name of a book? True or False?

True

 

60. Why is Lexie called Lexipedia?

Because she has a photographic memory

 

61. What disappointing ranking does Seattle Grace land at?

No. 12.

 

62. Who does Izzie begin seeing visions of?

Denny

 

63. Where does Derek propose to Meredith?

In the elevator

 

64. Who gets married in the 100th episode?

Alex and Izzie

 

65. What is Meredith’s address in the series?

613 Harper Lane

 

66. How does George reveal himself to Meredith when he’s injured?

He writes “007” in her palm.

 

67. What hospital does Seattle Grace merge with?

Mercy West

 

68. Which college did the show’s lead attend?

Dartmouth

 

69. Who does Jackson first develop feelings for?

Cristina

 

70. What is the name of Mark’s daughter?

Sloan

 

71. Why does Izzie leave “Grey’s Anatomy”?

She and Alex break up after she comes back from briefly running away.

 

72. What is the actual name of Jo’s Bar?

Emerald City Bar

 

73. What job does Ben have when he and Bailey first meet?

He’s an anesthesiologist

 

74. How does Jackson trick the hospital shooter into thinking Derek is dead?

He disconnects the heart monitor.

 

75. Who dies in the hospital shooting?

Percy and Reed, along with the gunman.

 

76. What unusual color is Cristina’s wedding dress?

Red

 

77. What nickname does Derek have for Amelia?

Amy

 

78. Which doctor temporarily quits surgery, and what new job do they take?

Cristina, a waitress at Joe’s

 

79. What type of alcohol was Yang’s and Mer’s favorite?

Tequila

 

80. Why does Teddy marry Henry?

To get him on her medical insurance.

 

81. What event sparks the musical episode?

Callie and Arizona get in a car crash.

 

82. Why did Meredith tamper with the Alzheimer’s trial?

To make sure that Adele got treatment and not a placebo.

 

83. Which actor has won a Tony award for her Broadway?

Sara Ramirez

 

84. What sport does the hospital field a team for?

Softball

 

85. When do Derek and Meredith officially get married?

Season 8

 

86. What medical condition does Zola have?

Spina bifida

 

87. Henry used to be what kind of professional athlete?

 

88. “Never diss anyone’s Juju”, who said these words?

Meredith Grey

 

89. In the alternate universe, who is Meredith engaged to?

Alex

 

90. Death always comes in what numbers?

Threes or Sevens

 

91. Andrew Deluca is diagnosed with what?

Bipolar Disorder

 

92. Who does April hook up with just before the board exams?

Jackson

 

93. Who became the face of the hospital?

Derek Shepherd

 

94. Which doctors are in the plane crash?

Meredith, Cristina, Derek, Mark, Lexie, and Arizona.

 

95. After the success of The Shepherd Method, what gift did McDreamy give Meredith?

A glow in the dark Kidney

 

96. Who was supposed to be on the plane, and who replaced them?

Alex was replaced by Arizona.

 

97. What state does Cristina move to?

Minnesota

 

98. Who is the O.B. that performs a C-section on Meredith?

Connie

 

99. What nickname do Meredith’s residents give to her?

“Medusa.”

100. Who dies on the same day as Bailey’s wedding?

Adele

 

101. What was Lexi’s full name?

Alexandra Grey

 

102. What activity does Derek use to retrain his hand after surgery?

Ping-pong

 

103. What names do Webber and Callie use when “undercover” at a rival hospital?

Julio and Calliope Plantain

 

104. Who gets electrocuted in the basement?

Webber and Heather

 

105. What condition does Bailey develop?

OCD

 

106. What important person calls Derek to ask for his expertise?

The President of the United States.

 

107. Who gave Derek the name McDreamy?

Cristina.

 

108. Why does Cristina lose the Harper Avery award?

Because she works at an Avery Foundation hospital.

 

109. Who was first nominated for a Harper Avery?

Cristina Yang

 

110. Which doctor goes with Cristina to her new hospital?

Ross

 

111. Who shot Derek in the show?

Gary Clark

 

112. Who does Cristina leave her shares of the hospital and her board position to?

Alex

 

113. Who did Jackson kick out of his OR when he wasn’t able to concentrate?

Miranda Bailey

 

114. What happened between Richard and Ellis at the carousel?

He broke up with her for good.

 

115. Who won the sparkle pager?

Meredith

 

116. What did April and Jackson name their son?

Samuel Norbert Avery

 

117. What complication happens after Dr. Herman’s tumor removal?

She’s left blind

 

118. How many sisters did Derek Shepherd have?

Four

 

119. At what age did Maggie graduate from Medical School?

Nineteen

 

120. What kind of doctor is Owen Hunt?

A medical army doctor and now a trauma surgeon

 

121. Who becomes Arizona’s roommate?

Andrew DeLuca

 

122. How is Callie’s new girlfriend connected to Meredith?

Penny was one of the doctors who failed to save Derek.

 

123. How many original characters are left as of season 17?

Four (always remember Bokhee)

 

124. What operation gets Ben in trouble?

Performing an emergency C-section in a hallway during a lockdown.

 

125. Who is awarded custody of Sofia?

Arizona

 

126. In season 1, which senior doctor’s significant other is never seen or referred to?

Adele, wife of Richard

 

127. Who does Owen ask to be his best man at his wedding to Amelia?

April

 

128. The episode where Derek dies is named after which song?

“How to Save a Life” by The Fray

 

129. Who accompanies Owen overseas on a military medical training program?

April

 

130. After the airplane crash, the name of the hospital is changed to what and after whom?

Grey Sloan Memorial for remembering crash victims Lexie Grey and Mark Sloan

 

131.Why doesn’t Alex have to take a plea deal?

DeLuca made the DA drop charges by threatening to give false testimony.

 

132. How many people died during the Clark shooting?

Eleven

 

133. What brings Maggie’s mother to the hospital?

Cancer

 

134. How many times did April get fired?

Twice

 

135. What does Alex do when he tracks down Jo’s abusive ex?

Nothing — he doesn’t even confront him.

 

136. When does Stephanie quit Grey Sloan?

After being burned in the fire.

 

137. What nickname did Meredith Grey earn from her interns?

Medusa

 

138. Whose sister is found alive?

Owen’s sister Megan

 

139. What career change does Ben decide to make?

He becomes a firefighter

 

140. Which patient and doctor got married for insurance reasons?

Henry and Teddy

 

141. What does Amelia discover about her own health?

She has a brain tumor

 

142. How many sisters does Meredith Grey have?

Three

 

143. How does Amelia know Koracick?

He was one of her professors.

 

144. Which three former characters have their “doppelgangers” show up in the 300th episode?

Cristina, George, and Izzie.

 

145. What award does Meredith win?

The Harper Avery.

 

146. Why does Sam Bello have to leave Seattle?

She’s a DACA recipient and ICE is trying to deport her.

 

147. Who officiates Alex and Jo’s wedding?

Meredith.

 

148. In Grey s Anatomy, Mer’s med school professor dies during which surgery?

Gallbladder Removal

 

149. Which show’s record did “Grey’s” surpass to become the longest-running primetime medical drama?

“ER.”

150. Who is the creator of the show?

Shonda Rhimes and Kristina Vernoff

 

151. What disease did Link have as a child?

Bone cancer.

 

152. Who plays the theme song of the show?

The Psapp

 

153. What second language does Meredith speak?

Italian

 

154. What was the name of the first episode of Grey s Anatomy?

Hard Day’s Night

 

155. What is the name of Alex’s mother?

Helen

 

156. What was the name of the doll with plastic organs?

Anatomy Jane

 

157. Who gets fired over Meredith’s insurance fraud?

Richard, Alex, and Meredith.

 

158. The stars of which old WB show reunite in a season 16 episode?

“Charmed.”

 

159. How many nieces and nephews does Derek have?

5 nephews and 9 nieces

 

160. Why does Koracick hate Halloween?

His son died just weeks before Halloween.

 

161. What doctor from Meredith’s past is on her license hearing panel?

The doctor who didn’t order a CT scan for Derek.

 

162. Meredith once dropped a heart. True or False?

False

 

163. When is the last time we see Alex?

At Meredith’s license hearing.

 

164. Why does Alex leave?

To be with Izzie, who used the frozen embryos from when they were married to have their children.

 

165. What party did Owen Hunt through to raise money for the hospital?

Carnival

 

166. Who is Teddy and Owen’s daughter named after?

Allison, Teddy’s best friend and former lover who died on 9/11.

 

167. What are the names of Alex’s siblings?

Amber and Aaron

 

168. What “present” does Cristina send Meredith?

Dr. Cormac Hayes.

 

169. Which dead characters did Meredith meet on her COVID “beach”?

Derek, George, Lexie, Mark, and DeLuca.

 

170. According to Dr. Thomas, what time is it in Moscow when it’s five in Seattle?

Four

 

171. How does Andrew DeLuca die?

He’s stabbed after confronting a child trafficker.

 

172. When does Meredith wake up from her COVID coma?

When Zola comes to visit her.

 

173. Who does Cristina stab with an epi?

Alex

 

174. Who does Jackson visit when he’s trying to decide the next steps in his life?

His father and April.

 

175. In season 6 in the episode “Sanctuary”, who was the second doctor that got shot?

Dr. Karev

 

176. What specialty does Jo switch to?

Ob-gyn.

 

177. This actress has portrayed Alexandra Grey on ‘Grey’s Anatomy’, starting in season 3. Who is she?

Chyler Leigh

 

178. When did we last see Nick Marsh before his return in season 18?

Season 14.

 

179. Which former main character returns?

Addison

 

180. Which intern paid off her debts with money she earned by modeling?

Izzie

 

181. Who officiates Owen and Teddy’s wedding?

Megan

 

182. Where does Meredith split her time between?

Seattle and Minnesota

 

183. What tragic event happens to Cristina on her wedding day in season three?

Seattle and Minnesota

 

184. What disease is Meredith’s new research focused on?

Parkinson’s.

 

185. Viewers were left in suspense at the end of the fifth season when George O’Malley and Izzie Stevens, both patients at the time, both flatlined as their friends frantically tried to save them. What was the outcome, as shown in the sixth season premiere, “Good Mourning”?

George died and Izzie lived

 

186. What hospital did they end up merging with?

Mercy West

 

187. Who does Meredith Grey date throughout the first five seasons (on/off relationship)?

Derek Shepherd

 

188. What design does Derek’s favorite scrub cap have on it?

Ferry boats

 

189. What is Derek Shepherd’s specialty?

Neurosurgery

 

190. In season 8 in the episode “Flight”, what did Cristina keep telling Meredith?

“I can’t find my shoe!”

 

191. What is Addison Montgomery’s specialty?

Neonatal surgery

 

192. Who was Meredith’s mother?

Ellis

 

193. What secret was Meredith keeping about her mother in Season 1?

That she had Alzheimer’s

 

194. Meredith’s father returned this season in “Tainted Obligation”, and he needed something from Meredith. A big something – what kind of organ transplant did Meredith and her father, Thatcher, undergo?

Liver transplant

 

195. What is Derek’s middle name?

Christopher

 

196. What injury did Mark Sloan sustain while having sex with Lexie?

A penile fracture

 

197. Later on, in the first season, Derek finally gives in to Meredith’s ultimatum “I want facts, and until I get them my pants are staying on!” One piece of information he gives her about himself is his favorite flavor of ice cream. What is it?

Coffee

 

198. In what other production did Patrick Dempsey and Kevin McKidd costar?

Made of Honor (2008)

 

199. Which intern died during the season premiere?

Heather Brooks

200. What is the name of Meredith’s dad?

Thatcher

 

201. What was the nickname George received from the other interns in the first season?

007

 

202. Why does Jo initially turn down Alex’s proposal?

Because she’s already married

 

203. How does Matthew propose to April?

With a flashmob

 

204. Which music superstar has a cat named after Meredith Grey?

 

205. Who did Richard turn over his job to when he stepped down as chief in season 8?

Owen

 

206. What season did the series stop using its opening theme sequence?

Season 2

 

207. What happened to Meredith during the episode in which a shooter entered the hospital to take revenge on the doctors?

She suffered a miscarriage

 

208. Which OG character does not visit Meredith on the beach in Season 17?

Christina Yang

 

209. Where did Meredith eventually dispose of her mother’s ashes?

Scrub room

 

210. Why did Izzie leave?

She got fired

 

211. Who was commonly referred to as “chief”?

Webber

 

212. In one episode of the sixth season, Dr. Shepherd deliberately disobeyed Chief Webber’s wishes by proceeding with an extremely risky surgery on a hospital employee. What was this employee/patient’s name?

Isaac

 

213. In “Kung Fu Fighting”, two women came into the ER. They were engaged in a contest that involved holding onto something; what was it?

A wedding dress

 

214. What is the name of the dog that Derek and Meredith shared in season two?

Doc

 

215. Derek Shepherd moved to Seattle from ____________.

New York

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